Minireview - Benefit of Isoflavone for Geriatrics

Isoflavone is a cheap, easily found diet that possible to be consumed on regular basis. Many epidemiological studies and animal experiments as well as clinical trial studies have proved the beneficial effects of isoflavones. However, no large meta-analysis study available to prove significantly. Isoflavones are believed to have the effect of decreasing the menopausal symptoms, prevent osteoporosis, prevent cardiovascular event, and even prevent breast and prostate cancer. Isoflavones mechanism of action including numerous pathways to reach the effects, but still being a challenge to be investigated further. Isoflavones are expected to replace HRT in the future that have been shown to have a very high risk of malignancy. Further clinical studies in larger scale and also biomolecular research are needed to prove the isoflavones benefit for the elderly population.